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Hypermobility spectrum disorders: A review.
1Rheumatology, Singing River Health System, 3603 Bienville Blvd, Ocean Springs, MS 39564, USA.
Joint hypermobility (JH) pain is now classified under hypermobility spectrum disorders (HSDs), updating previous terminology. Diagnosis involves JH with secondary musculoskeletal issues, excluding hypermobile Ehlers-Danlos syndrome (hEDS).
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Area of Science:
- Rheumatology
- Genetics
- Pain Management
Background:
- Joint hypermobility (JH) diagnosis and management have evolved.
- Previous terms like benign joint hypermobility syndrome (JHS) are updated.
- Genetic advances led to revised Ehlers-Danlos syndrome (EDS) classifications.
Purpose of the Study:
- Explain the nomenclature update from JHS to hypermobility spectrum disorders (HSDs).
- Detail musculoskeletal and extra-articular manifestations of HSD subtypes.
- Provide guidance on diagnosing and treating HSDs.
Main Methods:
- Literature review on joint hypermobility and related disorders.
- Analysis of updated diagnostic criteria for HSDs.
- Synthesis of current treatment strategies for HSDs.
Main Results:
- Hypermobility spectrum disorders (HSDs) encompass JH with secondary musculoskeletal issues, excluding hypermobile Ehlers-Danlos syndrome (hEDS).
- Extra-articular manifestations are frequent in HSD subtypes.
- Multidisciplinary management, lifestyle changes, physical therapy, and pharmacologic interventions are key.
Conclusions:
- The updated nomenclature clarifies the diagnosis of JH-related conditions.
- Understanding HSD manifestations guides clinical practice.
- A comprehensive, multidisciplinary approach optimizes HSD management.