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The Thyroid Gland01:23

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
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Related Experiment Video

Updated: Jul 18, 2025

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
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[Basicervical ectopic goiter associated with a eutopic thyroid gland: a case report].

Ndongo Pilor1, Moustapha Ndiaye2, Marie Joseph Dieme1

  • 1Centre Hospitalier National Universitaire de Fann, Université Cheikh Anta Diop, Dakar, Sénégal.

The Pan African Medical Journal
|August 28, 2023
PubMed
Summary

This case report details a rare instance of ectopic thyroid tissue found in the basicervical region alongside a eutopic goiter. Histology confirmed the diagnosis, highlighting its importance in diagnosing cervical masses.

Keywords:
Thyroid glandbasicervicalcase reportectopia

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Area of Science:

  • Endocrinology
  • Anatomic Pathology

Background:

  • The thyroid gland, an endocrine organ, regulates energy and phosphocalcic metabolism.
  • Typically located in the anterior cervical and pretracheal regions, ectopic thyroid tissue is a rare occurrence.
  • Ectopic thyroid is most commonly found in the basilingual area.

Observation:

  • A patient presented with a goiter in the normal cervical position (eutopic).
  • Additionally, ectopic thyroid tissue was identified in the basicervical position.
  • Surgical exploration via cervicotomy revealed the ectopic nodule.

Findings:

  • Histological examination confirmed the presence of ectopic thyroid tissue.
  • This dual presentation of eutopic and ectopic thyroid tissue is highly unusual.

Implications:

  • This case underscores the importance of considering ectopic thyroid tissue in the differential diagnosis of cervical masses.
  • Accurate diagnosis is crucial for appropriate patient management and treatment strategies.