Antimicrobial Photodynamic Therapy in the Approach of Complication After Implantation of Spiculated Polydioxanone

Gabriela V Carrasco1, Luciane Hiramatsu Azevedo1, Alessandro C da Silva2

  • 1Restorative Dentistry, School of Dentistry/University of São Paulo, São Paulo, BRA.

Cureus
|August 28, 2023
PubMed

Insights

Antimicrobial photodynamic therapy (aPDT) effectively treated a facial infection following polydioxanone (PDO) thread implantation. This safe and simple treatment using a low-level laser and methylene blue shows promising results for post-procedure complications.

Area of Science:

  • Dermatology
  • Biomedical Engineering

Background:

  • Polydioxanone (PDO) threads are widely used in non-surgical cosmetic facial procedures.
  • Complications such as infection can occur after PDO thread implantation.
  • Standard treatments may require adjunctive therapies for effective management.

Observation:

  • A 72-year-old female patient developed a facial infection post-mandible angle PDO thread implantation.
  • Following local drainage, antimicrobial photodynamic therapy (aPDT) was administered.
  • aPDT involved a 660 nm low-power laser and 0.01% methylene blue photosensitizer.

Findings:

  • Two daily sessions of aPDT were performed.
  • The infected region showed significant improvement within 48 hours, becoming dry and without secretion.
  • The patient experienced no adverse effects from the aPDT treatment.

Implications:

  • Antimicrobial photodynamic therapy (aPDT) presents a promising and effective treatment for infections after PDO thread implantation.
  • aPDT is a safe technique with low complexity and no adverse effects.
  • This approach offers a viable alternative for managing complications in aesthetic procedures.