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Antimicrobial Photodynamic Therapy in the Approach of Complication After Implantation of Spiculated Polydioxanone
Gabriela V Carrasco1, Luciane Hiramatsu Azevedo1, Alessandro C da Silva2
1Restorative Dentistry, School of Dentistry/University of São Paulo, São Paulo, BRA.
Abstract:
The present manuscript is a clinical case report in which antimicrobial photodynamic therapy (aPDT) - using a low-power laser (660 nm) associated with methylene blue photosensitizer (0.01%) - was considered for treating a case of complication after implantation of spiculated polydioxanone (PDO) threads, an aesthetic procedure worldwide performed in facial cosmetic non-surgical procedures. A 72-year-old female patient presented an infection in the face region where the PDO thread was implanted (mandible angle). After divulsion and local drainage, it was decided to associate aPDT using a low-level laser associated with a 0.01% methylene blue photosensitizer. Two sessions of aPDT were performed - on sequential days - and within 48 hours the region was dry and without signs of secretion. The use of aPDT seems to be a promising and effective option in cases of infections after implantation of PDO threads, consisting of a safe technique, of low execution complexity and without adverse effects.
Insights
Antimicrobial photodynamic therapy (aPDT) effectively treated a facial infection following polydioxanone (PDO) thread implantation. This safe and simple treatment using a low-level laser and methylene blue shows promising results for post-procedure complications.
Area of Science:
- Dermatology
- Biomedical Engineering
Background:
- Polydioxanone (PDO) threads are widely used in non-surgical cosmetic facial procedures.
- Complications such as infection can occur after PDO thread implantation.
- Standard treatments may require adjunctive therapies for effective management.
Observation:
- A 72-year-old female patient developed a facial infection post-mandible angle PDO thread implantation.
- Following local drainage, antimicrobial photodynamic therapy (aPDT) was administered.
- aPDT involved a 660 nm low-power laser and 0.01% methylene blue photosensitizer.
Findings:
- Two daily sessions of aPDT were performed.
- The infected region showed significant improvement within 48 hours, becoming dry and without secretion.
- The patient experienced no adverse effects from the aPDT treatment.
Implications:
- Antimicrobial photodynamic therapy (aPDT) presents a promising and effective treatment for infections after PDO thread implantation.
- aPDT is a safe technique with low complexity and no adverse effects.
- This approach offers a viable alternative for managing complications in aesthetic procedures.

