Related Experiment Video

Updated: Jul 18, 2025

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

24.3K

Myocarditis and Myocardial Injury in Long COVID Syndrome: A Comprehensive Review of the Literature

Sai Sri Hari Paruchuri1, Umm E Farwa2, Shaista Jabeen3

  • 1Internal Medicine, Dr. Pinnamaneni Siddhartha Institute of Medical Sciences and Research Foundation, Vijayawada, IND.

Cureus
|August 28, 2023
PubMed

Insights

Long COVID can cause serious heart problems like myocardial injury and myocarditis in people of all ages. Early detection and management are crucial for better outcomes in cardiovascular complications.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Coronavirus disease 2019 (COVID-19) has led to widespread health issues globally.
  • Long COVID, a persistent condition post-infection, affects diverse age groups and physiological systems.
  • Cardiovascular complications are a significant concern in long COVID patients.

Purpose of the Study:

  • To review the association between long COVID and cardiovascular complications, specifically myocardial injury and myocarditis.
  • To examine the prevalence and risk factors of these cardiac issues in long COVID.
  • To discuss diagnostic methods and therapeutic strategies for COVID-19-related myocarditis.

Main Methods:

  • Literature review focusing on studies linking long COVID to cardiovascular sequelae.
  • Analysis of diagnostic techniques including ECG, troponin levels, MRI, and endomyocardial biopsy.
  • Examination of current treatment guidelines and risk factor identification.

Main Results:

  • Myocardial injury in long COVID stems from direct cellular damage and T-cell responses, indicated by elevated cardiac biomarkers.
  • Myocarditis diagnosis can be aided by ECG, troponin, and MRI, with endomyocardial biopsy as the gold standard.
  • Identifying specific risk factors for cardiovascular complications in long COVID patients is essential.

Conclusions:

  • Effective screening for vulnerable populations and further research into the long-term physical health impacts of long COVID are critical.
  • Guideline-directed medical therapy and comprehensive care management improve prognosis for COVID-19 myocarditis.
  • Understanding and addressing cardiovascular complications are vital for managing the long-term burden of COVID-19.

Keywords:
acute myocardial injurycardiac outcomescardiovascular side effectscovid 19covid and cardiovascular complicationscovid and myocarditiscovid-induced myocarditissars-cov-2

More Related Videos

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse12:24

Noninvasive Assessment of Cardiac Abnormalities in Experimental Autoimmune Myocarditis by Magnetic Resonance Microscopy Imaging in the Mouse

Published on: June 20, 2014

10.0K
Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts08:51

Author Spotlight: Integrated Multi-Omics Analysis for Unveiling Multicellular Immune Signatures in Clinical Heart Attack Cohorts

Published on: September 20, 2024

1.3K

Related Concept Videos

Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
12
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
9
Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
7
Myocarditis IV: Nursing Management01:22

Myocarditis IV: Nursing Management

Myocarditis is an inflammatory condition of the myocardium requiring meticulous nursing management for optimal patient outcomes. Effective management begins with a thorough assessment of the patient's medical history, paying close attention to past infections, autoimmune disorders, travel history, and exposure to toxins or drugs. Recent viral infections and systemic diseases are particularly relevant due to their potential role in triggering myocarditis.Physical Examination and MonitoringThe...
13
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
20
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
10