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Revisiting the Mucosa of the Gastric Cardia: A Scope to Modify an Upper Gastrointestinal Endoscopy

Sudipta D Baruah1, Bishwajeet Saikia1, Raktim P Tamuli2

  • 1Anatomy, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, IND.

Cureus
|August 28, 2023
PubMed

Insights

Cardiac mucosa (CM) increases with age, suggesting a link to occult reflux. This finding may necessitate revised upper gastrointestinal endoscopy approaches.

Area of Science:

  • Gastroenterology
  • Histopathology
  • Forensic Medicine

Background:

  • Cardiac mucosa (CM) is often considered normal but its prevalence and relationship with age are not fully understood.
  • Studies suggest CM may develop due to occult reflux, particularly in older individuals.
  • The distribution of CM, oxyntic mucosa (OM), and oxyntocardiac mucosa (OCM) across different age groups requires further investigation.

Purpose of the Study:

  • To investigate the distribution of cardiac mucosa (CM), oxyntic mucosa (OM), and oxyntocardiac mucosa (OCM) in different age demographics.
  • To determine the correlation between age and the prevalence of CM in the stomach's cardiac region.

Main Methods:

  • Histological specimens were prepared from stomach samples.
  • The types of gastric mucosa (CM, OM, OCM) were identified and recorded.
  • The distribution of these mucosal types was analyzed across various age groups.

Main Results:

  • A significant variation in mucosal distribution was observed among different age groups.
  • The frequency of cardiac mucosa (CM) was found to increase with advancing age.

Conclusions:

  • The prevalence of cardiac mucosa (CM) increases significantly with age.
  • This age-related increase in CM supports the hypothesis that occult reflux contributes to its development.
  • Findings suggest a need to re-evaluate current upper gastrointestinal endoscopy protocols.

Keywords:
adenocarcinomabarrett’s esophaguscarcinoma esophaguscardiac mucosaendoscopygastric cardiagastroesophageal junctiongerd

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