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Related Experiment Videos

Urine-compatible polymer for long-term ureteral stenting.

J F Cardella, W R Castaneda-Zuniga, D W Hunter

    Radiology
    |November 1, 1986
    PubMed
    Summary

    This study evaluated C-Flex ureteral stents, finding an 80% patency rate. Strategies like increased fluid intake and antibiotics optimized stent function in patients.

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    Clinical endpoints in peripheral endovascular revascularization trials: a case for standardized definitions.

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2008

    Area of Science:

    • Urology
    • Biomaterials Science

    Background:

    • Internal double-J ureteral stents are crucial for maintaining urinary tract patency.
    • The development of durable, urine-compatible stent materials is an ongoing area of research.

    Purpose of the Study:

    • To assess the patency rate and durability of internal double-J ureteral stents made from a urine-compatible polymer (C-Flex).
    • To identify factors influencing stent patency and failure.
    • To compare the physical properties of urine-exposed stents with control materials.

    Main Methods:

    • 35 C-Flex ureteral stents were implanted in patients.
    • Stent patency was monitored over a follow-up period of 2 to 16 months (mean 5.0 months).
    • Physical properties of used stents were compared to virgin and shelf-aged tubing.

    Main Results:

    • An overall patency rate of 80% was achieved for the C-Flex stents.
    • Most stent failures occurred within the first 2 months.
    • No instances of stent migration or fracture were observed.
    • Physical properties remained stable after urine exposure.

    Conclusions:

    • C-Flex ureteral stents demonstrate promising patency and durability.
    • Optimizing urine flow and avoiding placement in infected systems can enhance stent performance.
    • Further research into biomaterial properties and clinical outcomes is warranted.

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