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Updated: Jul 27, 2026

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery
11:07

A Murine Model of Myocardial Ischemia-reperfusion Injury through Ligation of the Left Anterior Descending Artery

Published on: April 10, 2014

Inadvertent ligation of the left pulmonary artery

R B Jaffe, G S Orsmond, L G Veasy

    Radiology
    |November 1, 1986
    PubMed

    Insights

    Accidental ligation of the left pulmonary artery during patent ductus arteriosus closure is a rare complication. Diagnosis can be achieved through imaging techniques like chest radiography and echocardiography, enabling timely intervention.

    Area of Science:

    • Cardiovascular Surgery
    • Pediatric Cardiology
    • Diagnostic Imaging

    Background:

    • Patent ductus arteriosus (PDA) is a common congenital heart defect in neonates.
    • Surgical or interventional closure of PDA is a standard procedure.
    • Inadvertent ligation of the left pulmonary artery is a potential surgical complication.

    Purpose of the Study:

    • To report a series of patients who experienced inadvertent left pulmonary artery ligation.
    • To describe the diagnostic methods used to identify this complication.
    • To highlight the importance of prompt diagnosis and management.

    Main Methods:

    • Review of five pediatric patients with inadvertent left pulmonary artery ligation.
    • Analysis of diagnostic findings from chest radiography, two-dimensional echocardiography with Doppler spectral analysis, and angiography.
    • Evaluation of imaging features suggesting asymmetric pulmonary blood flow.

    Main Results:

    • The complication was diagnosed between 1 day and 5 years post-surgery.
    • Chest radiography suggested the diagnosis in three patients due to asymmetric pulmonary blood flow.
    • Two-dimensional echocardiography with Doppler and angiography confirmed the diagnosis in the remaining patients.

    Conclusions:

    • Inadvertent left pulmonary artery ligation is a serious complication of PDA closure.
    • Radiography, echocardiography with Doppler, and angiography are crucial for diagnosis.
    • Early detection and intervention are vital for patient outcomes.

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