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Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

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Published on: September 29, 2017

Hydrogels based on seafood chitin: From extraction to the development.

Juanni Zhang¹, Farhan Mohd Said¹, Zhanxin Jing²

¹Faculty of Chemical and Process Engineering Technology, Universiti Malaysia Pahang Al-Sultan Abdullah, Lebuh Persiaran Tun Khalil Yaakob, 26300 Kuantan, Pahang, Malaysia.

International Journal of Biological Macromolecules

|August 28, 2023

Summary

Sustainable chitin extraction from seafood waste and chitin hydrogel applications face challenges. This review evaluates novel extraction methods and hydrogel preparation, offering insights for future research and development.

Keywords:

Chitin extraction Hydrogels Seafood waste

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Area of Science:

Biomaterials Science
Sustainable Chemistry
Waste Valorization

Background:

Chitin, a biopolymer from seafood waste, offers biodegradable and non-toxic properties for diverse applications.
Traditional chemical chitin extraction methods have significant drawbacks.
Novel extraction techniques are emerging to address these limitations.

Purpose of the Study:

To review and evaluate sustainable chitin extraction methods from seafood waste.
To discuss the preparation and applications of chitin and its derivatives-based hydrogels.
To identify challenges and prospects in chitin extraction and hydrogel development.

Main Methods:

Comparative analysis of various chitin extraction techniques (enzymatic, microbial, ultrasonic, ionic liquids, etc.).
Evaluation of extraction methods based on yield, degree of acetylation, and residual protein/minerals.
Review of chitin and derivative hydrogel preparation strategies and their properties.

Main Results:

Novel extraction methods show promise but have limitations.
Chitin-based hydrogels exhibit excellent properties but face preparation challenges.
Each extraction method presents unique advantages and disadvantages regarding efficiency and purity.

Conclusions:

Selecting appropriate chitin extraction methods from seafood waste is crucial.
Further research is needed to overcome limitations in chitin hydrogel preparation and application.
Sustainable chitin utilization requires addressing extraction efficiency and hydrogel development challenges.