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Updated: Jul 17, 2025

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Central line associated and primary bloodstream infections
Adam G Stewart1, Kevin B Laupland2,3, Alexis Tabah1,2,4
1Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Royal Brisbane and Women's Hospital Campus, Brisbane.
Catheter-associated bloodstream infections (CA-BSIs) are common in ICUs, impacting patient outcomes. Effective prevention bundles and prompt catheter removal are crucial for reducing mortality and improving care for critically ill patients.
Area of Science:
- Infectious Diseases
- Critical Care Medicine
- Epidemiology
Background:
- Primary and intravascular catheter-associated bloodstream infections (CA-BSIs) are significant causes of morbidity and mortality in intensive care units (ICUs).
- Understanding the epidemiology and management of these infections is critical for improving patient outcomes in critically ill populations.
Conclusions:
- Primary BSIs are prevalent in ICU cohorts and negatively impact outcomes.
- Surveillance of BSIs in ICUs is essential for healthcare planning, prevention strategies, resistance tracking, and pathogen detection.
- Implementing evidence-based prevention bundles and ensuring timely source control are key to managing CA-BSIs and improving patient survival.
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