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Review: Discogenic Back Pain: Update on Treatment.
Edgar Remotti1, Chinoso Nduaguba1, Parker A Woolley1
1Beth Israel Deaconess Medical Center, Department of Anesthesiology, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA.
Orthopedic Reviews
|August 29, 2023
Summary
Discogenic back pain (DBP) is a common cause of lower back pain (LBP) resulting from disc degeneration. Treatment involves conservative measures, with ongoing research into novel therapies like biologics for improved efficacy.
Area of Science:
- Orthopedics
- Pain Management
- Regenerative Medicine
Background:
- Lower back pain (LBP) affects 80% of the US population.
- Discogenic back pain (DBP) arises from intervertebral disc degeneration without herniation.
- Diagnosis involves clinical evaluation and imaging (MRI, CT/provocative discography).
Purpose of the Study:
- To review current and emerging treatments for discogenic back pain (DBP).
- To highlight the challenges posed by limited DBP-specific treatment data.
- To explore the potential of novel therapeutic approaches for DBP.
Main Methods:
- Review of existing literature on DBP and chronic LBP (CLBP) treatments.
- Analysis of conservative management strategies (behavioral, pharmacologic, non-pharmacologic).
- Consideration of invasive therapies for select cases and novel biologic agents.
Main Results:
- DBP treatment often extrapolates from CLBP data due to limited DBP-specific research.
- Conservative treatments form the cornerstone of DBP management.
- Biologics represent a promising area for future DBP treatment research.
Conclusions:
- Effective DBP management requires a comprehensive, individualized approach.
- Further research is crucial to establish optimal treatment regimens for DBP.
- Novel therapies, including biologics, warrant further investigation for DBP treatment efficacy.
