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Type 2 diabetes and cognitive performance in middle age: a cross-sectional study
Teppo Sola1,2, Elina Pimiä2,3, Elina Lahti2
1Faculty of Social Sciences, Tampere University, Tampere, Finland.
Journal of Clinical and Experimental Neuropsychology
|August 29, 2023
Summary
Middle-aged individuals with type 2 diabetes showed no significant cognitive differences compared to healthy controls. This study found no meaningful evidence of cognitive decrements in patients with type 2 diabetes.
Area of Science:
- Neuroscience
- Endocrinology
- Psychology
Background:
- Type 2 diabetes is linked to cognitive decline in middle age.
- Previous studies had small sample sizes and varied methodologies.
- Few studies matched participants on key demographics like age, education, and gender.
Purpose of the Study:
- To investigate cognitive performance in middle-aged Finnish individuals with type 2 diabetes.
- To compare cognitive function between type 2 diabetes patients and matched healthy controls.
Main Methods:
- A cross-sectional matched pairs study design was employed.
- A comprehensive neuropsychological test battery (16 tests, 21 outcomes) was administered.
- 28 type 2 diabetes patients were matched with 28 healthy controls on age, education, and gender, with strict exclusion criteria.
Main Results:
- No significant differences were observed between groups in cognitive tests assessing attention, executive functions, memory, processing speed, and working memory.
- Subjective cognitive symptoms, anxiety, depression, burnout, fatigue, and alcohol use disorder symptoms did not differ between groups.
- Effect sizes for all measures were negligible to small, with a mean effect size of -0.12.
Conclusions:
- This study found no significant cognitive differences between middle-aged type 2 diabetes patients and carefully matched healthy individuals.
- The findings suggest that type 2 diabetes may not significantly impact cognitive function in middle age when controlling for confounding factors.
Keywords:
Cognitive decrementsdiabetes mellitusmiddle adulthoodneuropsychological assessmenttype 2 diabetesMore Related Videos
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