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Updated: Jul 17, 2025
Transplantation of Olfactory Ensheathing Cells to Evaluate Functional Recovery after Peripheral Nerve Injury
Published on: February 23, 2014
Olfactory Groove Schwannoma or Olfactory Ensheathing cell Tumor?
Wenqiang Guo1, Zhirui Liu2, Zhigang Wang1
1Department of Neurosurgery.
Background:
Schwannomas are benign tumors that arise from Schwann cells. Rare cases are shown to arise from the olfactory nerve. The genesis of Olfactory groove schwannoma (OGSs) is still puzzling. Yusda et al hypothesized that olfactory ensheathing cell tumors (OECTs) might be the origin of OGSs.
Clinical Presentation:
Here, the authors report the case of a 59-year-old woman who presented with a paroxysmal headache for 1 year. The tumor appeared as hypointensity on T1-weighted images, hyperintensity on T2-weighted, and exhibited strong, heterogeneous enhancement. The tumor was removed through a lateral supraorbital approach. The final pathologic diagnosis was schwannoma. The postoperative period was uneventful after 4 months, and the headache disappeared.
Disscussion And Conclusion:
OGSs and OECTs are extremely rare. There are many similarities in clinical manifestations, images, and pathologic findings. OGSs are difficult to distinguish from OECTs.
