A simple method of granulocyte enrichment of crude white cell suspensions labelled with 111In

A simple method of granulocyte enrichment of a 111In-labelled mixed white cell suspension is described. The method rests on preferential sedimentation by gravity of the granulocytes during labelling. In the 50 studies performed, the granulocytes constituted on average 90% of the 111In-labelled white cells injected for abscess detection. The modest degree of artefactual granulocyte pooling in the lungs and the results of the scintigraphic studies suggest that the method described is well-suited for scintigraphic localization of infectious and inflammatory processes.