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Changes in self-reported suicidal ideation during treatment with electroconvulsive therapy: A retrospective cohort
James Luccarelli1,2, Daniel Humphrey3, Thomas H McCoy1,2
1Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.
Acta Psychiatrica Scandinavica
|August 29, 2023
Summary
Electroconvulsive therapy (ECT) significantly reduces suicidal ideation (SI) in patients with depression. Higher baseline SI severity and outpatient treatment were linked to persistent SI, indicating areas for targeted intervention.
Area of Science:
- Neuroscience
- Psychiatry
- Clinical Psychology
Background:
- Suicidal ideation (SI) is a prevalent and serious symptom in patients experiencing depressive disorders.
- Electroconvulsive therapy (ECT) is a common treatment for severe depression, often including patients with SI.
Purpose of the Study:
- To quantify the reduction in self-reported SI during electroconvulsive therapy (ECT).
- To identify factors associated with the persistence of SI in patients undergoing ECT.
Main Methods:
- A retrospective, single-center cohort study analyzed data from 2554 patients receiving ECT.
- Self-reported SI was assessed using the Quick Inventory of Depressive Symptomatology (QIDS) before and after ECT sessions (5 or 10).
- Logistic regression models identified factors associated with persistent SI.
Main Results:
- A significant reduction in SI was observed with ECT treatment (p < 0.001).
- 64.0% of patients with baseline SI reported resolution after ECT.
- Higher baseline SI severity and outpatient treatment status were associated with a greater likelihood of persistent SI.
Conclusions:
- Electroconvulsive therapy (ECT) demonstrates efficacy in reducing self-reported suicidal ideation (SI).
- Findings support the use of ECT for patients with SI, but further research is needed on its impact on suicidal behavior.
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