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[Mesenteric infarction. 17-year retrospective study].

P A Clavien, C Muller

    Schweizerische Medizinische Wochenschrift
    |July 19, 1986
    PubMed
    Summary
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    Mesenteric infarction (MI) treatment needs reconsideration due to high recurrence rates. Selective vasodilator injection may improve outcomes by counteracting post-ischemic vasoconstriction.

    Area of Science:

    • Gastroenterology
    • Vascular Surgery
    • Critical Care Medicine

    Context:

    • Mesenteric infarction (MI) is a critical condition with high mortality.
    • A significant portion of patients admitted with MI are inoperable.
    • Current curative therapies for MI have a high recurrence rate.

    Purpose:

    • To evaluate the outcomes of patients treated for mesenteric infarction.
    • To identify factors contributing to the high recurrence rate of MI.
    • To propose a revised therapeutic strategy for MI.

    Summary:

    • Of 81 patients with MI, 44 underwent curative therapy, with a 45% survival rate.
    • 32% of treated patients died from recurrent MI, and 23% from other causes.
    • High recurrence suggests post-ischemic vasoconstriction may drive progression.

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    Impact:

    • Findings necessitate a re-evaluation of current therapeutic strategies for MI.
    • Selective intra-arterial vasodilator injection is proposed to improve prognosis.
    • This approach may mitigate progression of mesenteric ischemia and reduce mortality.