Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reply to Huang and Dong: Clarifying the interpretation of rapid steroid effects in social recognition.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Cultural humility in the teaching and practice of clinical care.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology·2026
Same author

Lysergic acid diethylamide pretreatment prolongs brain-stimulation induced neural activity changes.

Brain stimulation·2026
Same author

A brain circuit of bidirectional modulation of social and nonsocial cognition by androgens and estrogens in male mice.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Back to our roots: Integrating wholistic research approaches in the study of medicinal plants and mushrooms.

Psychopharmacology·2026
Same author

An Open-Source Restraint System for Magnetic Resonance Imaging in Awake Rats.

eNeuro·2026

Related Experiment Video

Updated: Jul 17, 2025

Construction of Local Field Potential Microelectrodes for in vivo Recordings from Multiple Brain Structures Simultaneously
06:07

Construction of Local Field Potential Microelectrodes for in vivo Recordings from Multiple Brain Structures Simultaneously

Published on: March 14, 2022

3.1K

A Simple, Lightweight, and Low-Cost Customizable Multielectrode Array for Local Field Potential Recordings.

Richard Quansah Amissah1, Abdalla M Albeely2, Elise M Bragg3,4

  • 1Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.

Eneuro
|August 29, 2023
PubMed
Summary

Researchers developed an affordable, customizable 16-channel multielectrode array (CMEA) for simultaneous local field potential (LFP) recording in rats. This lightweight, easy-to-build array offers a cost-effective alternative for brain activity research.

Keywords:
electrodeselectrophysiologyin vivolocal field potentialmultielectrode array

More Related Videos

Author Spotlight: Unraveling Neural Communication and Circuit Interactions in Health and Disease
06:55

Author Spotlight: Unraveling Neural Communication and Circuit Interactions in Health and Disease

Published on: November 21, 2024

805
A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes
09:27

A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes

Published on: March 3, 2014

13.5K

Related Experiment Videos

Last Updated: Jul 17, 2025

Construction of Local Field Potential Microelectrodes for in vivo Recordings from Multiple Brain Structures Simultaneously
06:07

Construction of Local Field Potential Microelectrodes for in vivo Recordings from Multiple Brain Structures Simultaneously

Published on: March 14, 2022

3.1K
Author Spotlight: Unraveling Neural Communication and Circuit Interactions in Health and Disease
06:55

Author Spotlight: Unraveling Neural Communication and Circuit Interactions in Health and Disease

Published on: November 21, 2024

805
A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes
09:27

A Method for Systematic Electrochemical and Electrophysiological Evaluation of Neural Recording Electrodes

Published on: March 3, 2014

13.5K

Area of Science:

  • Neuroscience
  • Bioengineering
  • Electrophysiology

Background:

  • Local field potential (LFP) recording is crucial for understanding brain communication and rhythmic activity.
  • Existing electrode methods for LFP data collection can be costly, complex to fabricate, and lack adaptability for multi-region or simultaneous recordings.
  • There is a need for accessible and versatile tools to study neural activity in research settings.

Purpose of the Study:

  • To describe the building process for a 16-channel customizable multielectrode array (CMEA).
  • To present a cost-effective and adaptable solution for simultaneous LFP recording from multiple brain regions in rats.
  • To highlight the CMEA's utility for preliminary neural activity studies.

Main Methods:

  • Detailed fabrication protocol for a 16-channel customizable multielectrode array (CMEA).
  • Characterization of CMEA properties including weight (<1 g) and build time (<1 h).
  • Demonstration of CMEA's compatibility with wired and wireless neural data acquisition systems for LFP, single-unit, and multiunit activity recording.

Main Results:

  • The developed CMEA is lightweight, quick to build, and highly affordable (approx. $15 CAD).
  • The CMEA enables simultaneous LFP recording from multiple brain regions in freely behaving rats.
  • The array can be adapted to record single-unit and multiunit activity, offering versatility.

Conclusions:

  • The described CMEA provides a simple, low-cost, and efficient alternative to commercial multielectrode arrays.
  • This customizable array facilitates preliminary studies of neural activity, reducing the barrier to entry for researchers.
  • The CMEA enhances the accessibility of multi-region brain activity recording in electrophysiology research.