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[Relation between respiratory function, bronchial reactivity and symptoms in heavy smokers]
Schweizerische Medizinische Wochenschrift
|September 13, 1986
Summary
Nearly half of heavy smokers exhibit bronchial hyperresponsiveness (BHR), a condition similar to asthma. This BHR was not linked to smoking intensity but correlated with lung function in those affected.
Area of Science:
- Pulmonary Medicine
- Respiratory Physiology
Context:
- Investigating airway morphology in heavy smokers undergoing thoracic surgery.
- Assessing bronchial hyperresponsiveness (BHR) in relation to smoking history and allergy symptoms.
Purpose:
- To determine the prevalence of BHR in heavy smokers.
- To explore the relationship between BHR, smoking load, allergy history, and airway obstruction.
Summary:
- 45% of 22 male heavy smokers showed BHR, with histamine PD20 values similar to asthma ranges.
- BHR was not correlated with smoking pack-years, positive skin tests, or salbutamol response.
- Airway obstruction was present in half of the subjects, but BHR was independent of obstruction severity.
Impact:
- Findings suggest BHR in smokers may manifest differently than in asthmatics, with some lacking typical bronchoconstriction symptoms.
- Highlights the complex interplay between smoking, airway reactivity, and potential underlying conditions.