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Myocarditis III: Medical Management01:14

Myocarditis III: Medical Management

7
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
7
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

12
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
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Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

14
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
14
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

38
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
38
Immunological Memory01:23

Immunological Memory

665
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
665
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

16
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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Related Experiment Video

Updated: Jul 17, 2025

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
08:44

Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis

Published on: September 7, 2022

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Recurrent Erythema Multiforme Major Following COVID-19 Infection.

Kayla Rykiel1, Julian Melchor1, Ian Motie2

  • 1Medicine, Florida State University College of Medicine, Tallahassee, USA.

Cureus
|August 30, 2023
PubMed
Summary

Recurrent erythema multiforme (EM), a rare skin condition, was observed following COVID-19 infection. This case highlights a potential, though uncommon, link between the viral illness and severe mucocutaneous reactions.

Keywords:
coronavirus diseasecovid-19erythema multiforme majorerythema multiforme-like lesionsherpes simplexrecurrent erythema multiformesars-cov-2stevens-johnson syndrome

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Area of Science:

  • Dermatology
  • Infectious Diseases
  • Immunology

Background:

  • Erythema multiforme (EM) is an acute, immune-mediated mucocutaneous condition.
  • EM presents with diverse lesions, often leading to diagnostic challenges and delayed treatment.
  • COVID-19 infection has been associated with various dermatological manifestations.

Observation:

  • A case of recurrent erythema multiforme is detailed in a 34-year-old male with no prior medical history.
  • The patient experienced extensive oral and genital mucosal lesions, along with diffuse cutaneous involvement.
  • Recovery from the EM outbreak was notably prolonged.

Findings:

  • The study documents an unusual association between COVID-19 infection and the onset of recurrent erythema multiforme.
  • This case adds to the limited understanding of the correlation between SARS-CoV-2 and EM.
  • The patient's presentation underscores the potential for severe mucocutaneous reactions post-COVID-19.

Implications:

  • This case suggests a possible trigger role for COVID-19 in the development of erythema multiforme.
  • Further research is warranted to elucidate the immunological mechanisms linking SARS-CoV-2 and EM.
  • Clinicians should consider COVID-19 as a potential precipitant in patients presenting with unexplained erythema multiforme.