Related Experiment Video
Updated: Jul 24, 2026

The Synergistic Effect of Visible Light and Gentamycin on Pseudomona aeruginosa Microorganisms
Published on: July 2, 2013
Extensively drug-resistant Pseudomonas aeruginosa panophthalmitis from contaminated artificial tears
Taylor Wang1, Sumeet Jain2, Yoav Glidai3
1Dayton and Karen Brown Division of Infectious Diseases, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, 400 Community Dr, Manhasset, NY 11030, USA.
Abstract:
Pseudomonas aeruginosa is one of the common gram-negative organisms that cause severe invasive infections in different organ systems. P. aeruginosa has unique intrinsic mechanisms to develop antimicrobial resistance quickly, making it extremely difficult to treat. We report a case of extensively drug-resistant (XDR) P. aeruginosa panophthalmitis due to contaminated artificial tears. This report investigates the role of systemic and intravitreal antimicrobials, summarizes the resistance mechanisms of P. aeruginosa, and provides an overview on cefiderocol, a novel antimicrobial that targets multidrug-resistant (MDR) and XDR Gram-negative pathogens.
Insights
Extensively drug-resistant Pseudomonas aeruginosa from contaminated artificial tears caused severe eye infections. Treatment involved systemic and intravitreal antimicrobials, highlighting challenges in combating antimicrobial resistance.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Pseudomonas aeruginosa is a common gram-negative bacterium causing severe invasive infections.
- P. aeruginosa exhibits rapid development of antimicrobial resistance, complicating treatment.
- Contaminated medical products, such as artificial tears, can be a source of infection.
More Related Videos
Related Concept Videos
Ophthalmic Drug Delivery Systems
Microbiome of the Eye

