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Updated: Jul 17, 2025

Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
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Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients

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m6A-Mediated Biogenesis of circDDIT4 Inhibits Prostate Cancer Progression by Sequestrating ELAVL1/HuR

Zhe Kong1, Yali Lu1, Yue Yang1

  • 1Obstetrics and Gynecology Hospital of Fudan University, State Key Lab of Genetic Engineering, MOE Engineering Research Center of Gene Technology, School of Life Sciences, Key Laboratory of Reproduction Regulation of NPFPC (SIPPR, IRD), Fudan University, Shanghai, P.R. China.

Molecular Cancer Research : MCR
|August 30, 2023
PubMed
Summary

Circular RNA DDIT4 (circDDIT4) suppresses prostate cancer by sponging ELAVL1/HuR, reducing anoctamin 7 (ANO7) expression. N6-methyladenosine (m6A) modification regulates circDDIT4 levels, impacting cancer progression.

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