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Risk factors for late (28+ weeks' gestation) stillbirth in the United States, 2014-2015
Darren Tanner1, Sushama Murthy1, Juan M Lavista Ferres1
1AI for Good Research Lab, Microsoft Corporation, Redmond, WA, United States of America.
Plos One
|August 30, 2023
Summary
Late stillbirth is a significant concern in the US. High maternal body mass index (BMI) and fetal growth restriction are key risk factors, while nutritional programs show promise in reducing stillbirth burden.
Area of Science:
- Reproductive Health
- Maternal-Fetal Medicine
- Public Health
Background:
- Late stillbirth (≥28 weeks gestation) affects 2.72/1000 births in the US.
- Sociodemographic factors like race and maternal age influence stillbirth risk.
Purpose of the Study:
- Identify modifiable risk factors for late stillbirth.
- Determine factors contributing significantly to the stillbirth burden in the US.
Main Methods:
- Retrospective population-based study using US Centers for Disease Control and Prevention data (2014-2015).
- Analysis of over 6.7 million live births and 18,000 fetal deaths.
Main Results:
- High maternal body mass index (BMI) and infants small for gestational age were major contributors to stillbirth.
- Modifiable factors like delayed prenatal care, diabetes, hypertension, and smoking increased risk but accounted for a smaller percentage.
- Participation in the WIC program was linked to a 28% reduction in stillbirths.
Conclusions:
- High maternal BMI and fetal growth restriction are critical targets for stillbirth reduction.
- Expanding nutritional support programs can substantially decrease the stillbirth burden.
- Addressing obesity and fetal growth restriction alongside nutritional programs is key to reducing late stillbirths.
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