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The emerging role of IL-38 in diseases: A comprehensive review
Weijun Chen1,2, Shuangyun Xi1,2, Yong Ke1,2
1Center of Forensic Expertise, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, China.
Introduction:
Interleukin-38 (IL-38) is a new type of anti-inflammatory cytokine, which is mainly expressed in the immunity-related organs and is involved in various diseases including cardiovascular and cerebrovascular diseases, lung diseases, viral infectious diseases and autoimmune diseases.
Aim:
This review aims to detail the biological function, receptors and signaling of IL-38, which highlights its therapeutic potential in related diseases.
Conclusion:
This article provides a comprehensive review of the association between interleukin-38 and related diseases, using interleukin-38 as a keyword and searching the relevant literature through Pubmed and Web of science up to July 2023.
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