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Related Experiment Video

Updated: Jul 17, 2025

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Isolation and Differentiation of Stromal Vascular Cells to Beige/Brite Cells

Published on: March 28, 2013

Reconstructing human brown fat developmental trajectory in vitro.

Jyoti Rao¹, Yannis Djeffal¹, Jerome Chal¹

¹Department of Pathology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, 60 Fenwood Road, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.

Developmental Cell

|August 30, 2023

Summary

This summary is machine-generated.

Researchers identified a key GATA6 stage in brown adipocyte (BA) development. This finding enables efficient in vitro differentiation of human pluripotent stem cells into functional brown fat cells that generate heat.

Failed At:

2026-07-10T14:57:32.317391+00:00

Keywords:

GATA6 brown adipocytes brown adipose tissue directed differentiation human pluripotent stem cells metabolism obesity

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