Related Experiment Video
Updated: Jul 17, 2025

Detection of Viruses from Bioaerosols Using Anion Exchange Resin
Published on: August 22, 2018
Airborne virus transmission: Increased spreading due to formation of hollow particles
Gizem Ozler1, Holger Grosshans1
1Physikalisch- Technische Bundesanstalt (PTB), Braunschweig 38116, Germany; Otto von Guericke University of Magdeburg, Institute of Aparatus and Environmental Technology, Magdeburg 39106, Germany.
Abstract:
The globally supported social distancing rules to prevent airborne transmission of COVID-19 assume small saliva droplets evaporate fast and large ones, which contain most viral copies, fall fast to the ground. However, during evaporation, solutes distribute non-uniformly within the droplets. We developed a numerical model to predict saliva droplet drying in different environments. We represent saliva droplets as a solution of NaCl mixed with water. In a hot and dry ambiance, the solutes form a shell on the droplets' surface, producing light, hollow particles. These hollow particles have a larger cross-sectional area compared to their solid counterparts and can float longer and travel farther in the air. We introduced the "hollowness factor," which serves as a measure of the ratio of the volume of a hollow particle and the volume of a solid residue formed during droplet drying. Through our investigations, we determined that under specific conditions, namely an ambient humidity level of 10% and a temperature of 40°C, the highest hollowness factor observed was 1.610. This finding indicates that in the case of hollow particle formation, the droplet nucleus expands by a factor of 1.610 compared to its original size.
More Related Videos
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
External and Internal Respiration
Viral Recombination
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

