[Tendency toward bleeding in Noonan syndrome]

Bleeding tendency in Noonan-patients is only sporadically mentioned in literature. There is no equivocal opinion about its cause. By means of a questionnaire data were collected from 29 Noonan-patients, registered in our hospital. In about half of these patients these data indicated the existence of a bleeding tendency. Some of these patients revealed a marked thrombocytopathy characterised as a disturbance in secondary aggregation. Further research into the cause is desirable.