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Related Experiment Video

Updated: Jul 17, 2025

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues
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Zinner Syndrome: Radiologic Diagnosis in a Rare Case.

Derya Bas1, Mustafa Orhan Nalbant1

  • 1University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital Radiology Department.

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|August 31, 2023
PubMed
Summary

Zinner's syndrome, a rare congenital condition, involves seminal vesicle and urinary tract anomalies. Magnetic resonance imaging (MRI) is crucial for diagnosing this condition and differentiating seminal vesicle cysts from other pelvic masses.

Keywords:
Zinner syndromecross-sectional imagingejaculatory duct obstructionipsilateral renal hypoplasiatransrectal ultrasound

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Area of Science:

  • Urology
  • Radiology
  • Embryology

Background:

  • Zinner's syndrome is a rare congenital malformation involving the seminal vesicle and upper urinary tract, stemming from mesonephric duct developmental anomalies.
  • Diagnosis and management of Zinner's syndrome necessitate advanced imaging techniques to accurately assess the anatomical abnormalities.

Observation:

  • A 21-year-old male with a solitary kidney presented with abdominal pain, prompting imaging studies including ultrasonography, CT, and MRI.
  • MRI revealed a tubular, fluid-filled pelvic lesion consistent with a seminal vesicle cyst, alongside a hypoplastic left kidney.

Findings:

  • The imaging findings, particularly the MRI characteristics of the pelvic cyst and renal anomaly, led to the diagnosis of Zinner's syndrome.
  • The characteristic triad includes unilateral renal agenesis/hypoplasia, ipsilateral seminal vesicle cyst, and ejaculatory duct obstruction.

Implications:

  • Magnetic resonance imaging (MRI) is the gold standard for diagnosing Zinner's syndrome due to its superior soft tissue contrast resolution.
  • Accurate MRI depiction of male genital tract anatomy aids in distinguishing seminal vesicle cysts from other pelvic cystic masses, guiding appropriate therapeutic strategies.