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Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

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Reference equations for quadriceps strength, endurance and power: a multicentre study.

Sophie Tanguay¹, Didier Saey¹, Sarah Marklund²

¹Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Quebec City, QC, Canada.

ERJ Open Research

|August 31, 2023

Summary

Reference equations for quadriceps muscle function in COPD patients were developed. These equations show reduced muscle function in COPD patients and validate clinical measurements.

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Lower Limb Biomechanical Analysis of Healthy Participants

Lower Limb Biomechanical Analysis of Healthy Participants

Published on: April 15, 2020

Area of Science:

Pulmonary Medicine
Exercise Physiology
Biostatistics

Background:

Lower-limb muscle function assessment is crucial for COPD management but lacks established reference values.
This deficiency impedes clinical recommendations and accurate interpretation of patient measurements.

Purpose of the Study:

To develop reference equations for quadriceps strength, endurance, and power in healthy individuals.
To evaluate the construct validity of these reference values in patients with chronic obstructive pulmonary disease (COPD).

Main Methods:

Quadriceps strength, endurance, and power were measured in 158 healthy individuals and 87 COPD patients.
Reference equations were derived using multiple linear regression, incorporating age, sex, height, and BMI.
Construct validity was assessed by correlating muscle function (as % of predicted) with 6-minute walk test (6MWT) and 1-minute sit-to-stand test (1STS) performance in COPD patients.

Main Results:

Reference equations explained 50-70% of the variance in quadriceps properties in healthy individuals (excluding isometric endurance).
Patients with COPD demonstrated significantly reduced quadriceps strength, endurance, and power compared to predicted values.
Correlations between muscle function (as % of predicted) and 6MWT/1STS performance ranged from 0.28 to 0.49 (p<0.05), indicating construct validity.

Conclusions:

Developed reference equations provide a basis for assessing quadriceps muscle function in COPD.
The findings confirm reduced lower-limb muscle function in COPD patients.
The established construct validity supports the clinical utility of these reference values for COPD assessment.