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Comparative Analysis of Clinical Characteristics Between Cold-Dampness Syndromes and Heat-Dampness Syndrome
Objective:
This study investigates the clinical characteristics of patients with two acute Traditional Chinese Medicine (TCM) syndromes.
Methods:
A retrospective study between January 2016 and January 2020 was conducted. A total of 89 patients with acute gouty arthritis were admitted to our hospital and were divided into two groups: the cold-dampness syndrome (CDR) group (38 patients) and the heat-dampness syndrome (HDR) group (51 patients). The comparison includes the differences in fever (>37.3°C), procalcitonin (PCT), and C-reactive protein (CRP) between these two groups.
Results:
The results indicated significantly higher levels of CRP and PCT in the HDR group compared to the CDR group (P < .001). Age emerged as the independent variable associated considerably with PCT and CRP levels. There was a statistically significant difference in the number of tophus cases between the groups (P < .001), while no statistically significant differences were observed in joint effusion or the number of joint swelling and pain between the two groups.
Conclusions:
Our study reveals that in acute gout, fever, procalcitonin (PCT), and C-reactive protein (CRP) levels differ significantly between cold-dampness and heat-dampness syndromes, with no observed association with the presence of tophi.
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