Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

285
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
285
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

231
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
231
Irritable Bowel Syndrome I: Introduction01:17

Irritable Bowel Syndrome I: Introduction

311
Irritable Bowel Syndrome (IBS) is characterized by functional disturbances in the gastrointestinal system, presenting a cluster of symptoms without evident structural or biochemical abnormalities. It primarily affects the large intestine and may cause abdominal pain, bloating, excessive gas, diarrhea, constipation, or both.
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
311

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A national survey of emergency department syphilis screening and sexually transmitted infection testing and treatment practices.

The American journal of emergency medicine·2026
Same author

Protocol for a randomized trial of a scalable, interactive tool to support surrogate decision-makers of critically ill patients.

Contemporary clinical trials·2026
Same author

Lupus nephritis outcomes in Aotearoa New Zealand, a retrospective case series.

Lupus·2026
Same author

Excess cancer incidence and mortality among patients with systemic lupus erythematosus: a population-based study in New Zealand.

The New Zealand medical journal·2025
Same author

Advance care planning impact on caregivers and end-of-life care in advanced cancer.

Journal of the National Cancer Institute·2025
Same author

Efficacy and Safety of Risankizumab for Active Psoriatic Arthritis: 196-Week Results from the KEEPsAKE 1 and KEEPsAKE 2 Randomized Clinical Trials.

Rheumatology and therapy·2025

Related Experiment Video

Updated: Jul 17, 2025

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

708

Paraneoplastic sacroiliitis.

Uri Arad1,2, Charles Werren3, Douglas White4,2

  • 1Rheumatology, Waikato Hospital, Hamilton, New Zealand uri.arad@waikatodhb.health.nz.

BMJ Case Reports
|August 31, 2023
PubMed
Summary

This case report details a rare instance of paraneoplastic sacroiliitis, a condition mimicking polymyalgia rheumatica, associated with an underlying urothelial carcinoma. It highlights the importance of considering malignancy in persistent inflammatory conditions.

Keywords:
Musculoskeletal syndromesRheumatologyUrological cancer

More Related Videos

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.0K
C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position
12:25

C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position

Published on: September 16, 2022

4.0K

Related Experiment Videos

Last Updated: Jul 17, 2025

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

708
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

20.0K
C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position
12:25

C-arm-Free Simultaneous OLIF51 and Percutaneous Pedicle Screw Fixation in a Single Lateral Position

Published on: September 16, 2022

4.0K

Area of Science:

  • Rheumatology
  • Oncology
  • Urology

Background:

  • Polymyalgia rheumatica (PMR) is an inflammatory condition characterized by stiffness and aching in the shoulder and pelvic girdles.
  • Elevated C-reactive protein (CRP) levels are common in PMR, often leading to a presumptive diagnosis.
  • Standard PMR treatments may be ineffective in cases with underlying, undiagnosed pathologies.

Observation:

  • A 70-year-old male initially presented with symptoms suggestive of PMR, including shoulder and pelvic girdle stiffness and aching.
  • Despite prednisone treatment and immunosuppressive agents, his symptoms persisted with relapses.
  • Five years later, gross painless hematuria revealed an invasive papillary urothelial carcinoma.

Findings:

  • Staging CT scans showed bilateral erosive sacroiliitis, developing after the initial presentation.
  • The sacroiliitis was initially misdiagnosed as PMR due to overlapping symptoms and elevated CRP.
  • This represents the first reported case of paraneoplastic sacroiliitis associated with a solid tumor, specifically urothelial carcinoma.

Implications:

  • Paraneoplastic sacroiliitis is a rare but critical differential diagnosis in patients presenting with inflammatory symptoms suggestive of PMR.
  • Persistent or relapsing inflammatory conditions, even with elevated inflammatory markers, warrant thorough investigation for underlying malignancy.
  • Early detection of associated solid tumors is crucial for effective management and improved patient outcomes.