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Basilar artery occlusion location and clinical outcome: data from the ATTENTION multicenter registry

Shuai Yu1,2, Xiaocui Wang1, Zhiliang Guo1

  • 1Department of Neurology, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.

Journal of Neurointerventional Surgery
|August 31, 2023
PubMed

Insights

For acute basilar artery occlusion treated with endovascular therapy, proximal and middle occlusions are linked to worse outcomes and higher mortality compared to distal occlusions. This finding is crucial for predicting patient prognosis.

Area of Science:

  • Neurology
  • Vascular Surgery
  • Interventional Radiology

Background:

  • Acute basilar artery occlusion is a critical condition with significant morbidity and mortality.
  • Endovascular treatment is a primary intervention for acute basilar artery occlusion.

Purpose of the Study:

  • To investigate the impact of occluded vessel location on prognostic outcomes in patients undergoing endovascular treatment for acute basilar artery occlusion.
  • To compare outcomes across distal, middle, and proximal occlusion sites within the basilar artery.

Main Methods:

  • Analysis of patient data from the ATTENTION registry.
  • Comparison of baseline characteristics across different occlusion locations.
  • Application of univariable and multivariable regression analyses to determine the effect of occlusion location on outcomes.

Main Results:

  • 1672 patients were analyzed: 583 distal, 540 middle, 549 proximal occlusions.
  • Proximal and middle occlusions were significantly associated with unfavorable outcomes (mRS 0-3) and increased mortality compared to distal occlusions.
  • No association was found between occluded vessel location and symptomatic intracranial hemorrhage.

Conclusions:

  • Proximal and middle basilar artery occlusions are linked to poor clinical outcomes and increased mortality after endovascular treatment.
  • Occlusion location is a significant prognostic factor in acute basilar artery occlusion management.
Abstract

Keywords:
InterventionStrokeThrombectomy

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