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Related Concept Videos

Overview Of Cell Separation And Isolation01:20

Overview Of Cell Separation And Isolation

Cell separation was first achieved in 1964 by S. H. Seal, who separated large tumor cells from the smaller blood cells using filtration. Two years later, Pohl and Hawk performed experiments on how cells respond differently to a nonuniform electric field based on the cell type. Such observations were the inception of cell separation methods, which allow isolating a single cell type from a heterogeneous sample.
Microbial Biosensors01:17

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Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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Cell-Based Micro/Nano-Robots for Biomedical Applications: A Review.

Bo Chen1, Hongyan Sun1, Jiaying Zhang1

  • 1School of Mechanical Engineering and Automation, Beihang University, Beijing, 100191, China.

Small (Weinheim an Der Bergstrasse, Germany)
|September 1, 2023
PubMed
Summary

Cell-based micro/nano-robots offer unique advantages for biomedical applications like drug delivery and diagnostics. This review highlights their progress, actuation methods, and potential for precise medical treatments.

Keywords:
biomedical applicationsdrug delivery systemsexternal-propelledmicro/nano robots

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Robotics

Background:

  • Micro/nano-robots are versatile tools in biomedicine, utilized for disease diagnosis, tumor imaging, drug delivery, and targeted therapy.
  • Cell-based micro-robots possess distinct characteristics derived from their diverse cell origins.
  • The integration of various actuation methods, especially external propulsion, amplifies the potential of cell-based microrobots in medical applications.

Purpose of the Study:

  • To review recent advancements and applications of cell-based micro/nano-robots.
  • To summarize diverse actuation methods applicable to micro/nano-robots.
  • To introduce cell-based micro-robots utilizing different cellular templates.

Main Methods:

  • Summarization of various actuation techniques for micro/nano-robots.
  • Introduction of cell-based micro-robots based on different cell templates.
  • Focus on the precise control of cell-based micro/nano-robots using external fields.

Main Results:

  • Overview of current progress in cell-based micro/nano-robot technology.
  • Categorization of different actuation strategies for micro/nano-robots.
  • Exploration of precise control mechanisms for cell-based systems.

Conclusions:

  • Cell-based micro/nano-robots show significant promise for advanced biomedical applications.
  • Further research into actuation and control is crucial for clinical translation.
  • Challenges and future prospects for these advanced robotic systems are discussed.