Cryolipolysis for fat reduction using Cooltech® Define technology: A large-sample retrospective clinical study.

Area of Science:

• Dermatology
• Aesthetic Medicine
• Body Contouring

Background:

• Cryolipolysis is a noninvasive method for localized fat reduction.
• It selectively induces adipocyte apoptosis via controlled cold exposure.
• The Cooltech® device is a globally utilized system for this procedure.

Purpose of the Study:

• To assess the efficacy and safety of the Cooltech® Define system for localized fat removal.
• Evaluation across various body areas was conducted.

Main Methods:

• A retrospective, single-center study involving 287 patients.
• 1118 procedures were performed using Cooltech® Define on diverse body areas.
• Efficacy was measured by plicometry and photographic analysis; safety was monitored for side effects.

Main Results:

• Significant reduction in fold thickness by -69.91% (from 35.33 mm to 10.69 mm).
• Post-treatment pain reported in 1.70% of cases.
• One instance of paradoxical adipose hyperplasia (0.09%) was observed.

Conclusions:

• The Cooltech® Define device is a safe and effective nonsurgical option for localized fat reduction.
• The procedure is well-tolerated by patients.
• Cryolipolysis offers a reliable method for body contouring.