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Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA
Published on: December 19, 2019
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Papilliferous Keratoameloblastoma: Systematic review
Sanpreet S Sachdev1, Tabita J Chettiankandy1, Yogita B Adhane1
1Department of Oral Pathology and Microbiology, Government Dental College and Hospital, Mumbai, India.
Sultan Qaboos University Medical Journal
|September 1, 2023
Summary
Papilliferous keratoameloblastoma (PKA), a rare ameloblastoma variant, typically affects the right mandibular posterior region in older adults. Surgical resection and diligent follow-up are crucial for managing this aggressive tumor.
Area of Science:
- Oral pathology
- Odontogenic tumors
- Neoplasms of the jaw
Background:
- Papilliferous keratoameloblastoma (PKA) is a rare odontogenic tumor with limited understanding of its clinical and biological characteristics.
- Clarifying the clinicodemographic, radiological, and histopathological features of PKA is essential for accurate diagnosis and management.
Approach:
- A systematic literature review was conducted across multiple databases to identify and analyze case reports of PKA.
- The review focused on characterizing the demographic, clinical, radiological, and histopathological aspects of reported PKA cases.
Key Points:
- The review identified 10 PKA cases, with half originating from India.
- All cases occurred in the mandibular posterior region, predominantly on the right side.
- PKA predominantly affects individuals in their fifth decade or older.
Conclusions:
- Papilliferous keratoameloblastoma is considered an aggressive variant of conventional ameloblastoma.
- The tumor exhibits a predilection for the right mandibular posterior region in older individuals.
- Surgical resection combined with meticulous follow-up is the recommended treatment approach for PKA.
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