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The Inflamed Niche: A Double-Edged Sword in AML?

Livia E Lisi-Vega1,2,3, Simón Méndez-Ferrer1,2,3

  • 1National Health Service Blood and Transplant, Cambridge, United Kingdom.

Blood Cancer Discovery
|September 1, 2023
PubMed
Summary

Inflammation in acute myeloid leukemia (AML) bone marrow shifts stem and stromal cells toward a proinflammatory state. This shift may reduce relapse risk but also makes AML cells more vulnerable to treatment.

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