[Plasma volume changes in essential hypertension patients]

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Updated: Oct 21, 2026

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS
08:12

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS

Published on: November 26, 2018

I Tomov, A Elenkova

    Vutreshni Bolesti
    |January 1, 1986
    PubMed

    Insights

    Increased plasma volume is common in essential hypertension, impacting cardiac output and blood flow. These findings highlight plasma volume

    Area of Science:

    • Cardiovascular Physiology
    • Hypertension Research

    Background:

    • Essential hypertension involves complex hemodynamic alterations.
    • Understanding these changes is crucial for effective management.

    Purpose of the Study:

    • To investigate the role of plasma volume in essential hypertension.
    • To correlate plasma volume with other hemodynamic parameters.

    Main Methods:

    • Studied 180 patients with essential hypertension (WHO stages I-III).
    • Measured plasma volume, cardiac output, blood flow velocity, and total peripheral vascular resistance.

    Main Results:

    • Elevated plasma volume observed in most early-stage patients.
    • 36% of advanced-stage patients also showed increased plasma volume.
    • Plasma volume changes significantly influenced other hemodynamic indices.

    Conclusions:

    • Plasma volume is a key factor in hemodynamic dysregulation in essential hypertension.
    • Altered plasma volume contributes to the overall hemodynamic reorganization in hypertensive patients.

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