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[Plasma volume changes in essential hypertension patients]
Insights
Increased plasma volume is common in essential hypertension, impacting cardiac output and blood flow. These findings highlight plasma volume
Area of Science:
- Cardiovascular Physiology
- Hypertension Research
Background:
- Essential hypertension involves complex hemodynamic alterations.
- Understanding these changes is crucial for effective management.
Purpose of the Study:
- To investigate the role of plasma volume in essential hypertension.
- To correlate plasma volume with other hemodynamic parameters.
Main Methods:
- Studied 180 patients with essential hypertension (WHO stages I-III).
- Measured plasma volume, cardiac output, blood flow velocity, and total peripheral vascular resistance.
Main Results:
- Elevated plasma volume observed in most early-stage patients.
- 36% of advanced-stage patients also showed increased plasma volume.
- Plasma volume changes significantly influenced other hemodynamic indices.
Conclusions:
- Plasma volume is a key factor in hemodynamic dysregulation in essential hypertension.
- Altered plasma volume contributes to the overall hemodynamic reorganization in hypertensive patients.
Abstract:
Plasma volume, cardiac output, velocity of blood flow and total peripheral vascular resistance were studied in 180 patients with essential hypertension, stages I, II and III according to WHO classification. Increased plasma volume was established in the majority of the patients with early stage of the disease and in 36 per cent of the patients with advanced essential hypertension. The studies reveal that the changes in plasma volume are of importance for the deviations of the other hemodynamic indices and for the reorganization of the hemodynamics in the patients with essential hypertension.