Anesthetic Considerations in Multisystem Inflammatory Syndrome in Children: A Case Series

Area of Science:

• Pediatric critical care medicine
• Anesthesiology
• Immunology

Background:

• Multisystem inflammatory syndrome in children (MIS-C) is a post-infectious immune response associated with SARS-CoV-2.
• MIS-C can lead to multiorgan dysfunction and shock, posing significant challenges for surgical patients.
• Limited data exist on the anesthetic implications for children with MIS-C.

Purpose of the Study:

• To describe the anesthetic management challenges in children with MIS-C undergoing surgery.
• To share clinical experiences and dilemmas faced by anesthesiologists managing these complex cases.
• To enhance awareness of MIS-C-associated complications for perioperative care.

Main Methods:

• Case series review of three children with MIS-C undergoing emergency and elective surgery.
• Multidisciplinary team involvement in perioperative anesthetic planning and execution.
• Individualized, case-based decision-making tailored to organ system involvement and disease progression.

Main Results:

• Anesthetic management was dynamic, adapting to the specific organ systems affected by MIS-C.
• Perioperative care required careful consideration of potential complications related to MIS-C.
• Successful anesthetic management was achieved through collaborative, tailored approaches.

Conclusions:

• Anesthesiologists must be aware of MIS-C complications for effective perioperative management.
• Individualized anesthetic strategies are crucial for children with MIS-C undergoing surgery.
• Further research is needed to establish best practices for anesthetic care in MIS-C patients.