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Updated: Jul 17, 2025
Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published on: July 16, 2018
Anatomical landmarks during high-magnification microsurgery for a safe and effective resection of high-grade gliomas:
Arianna Fava1,2, Paolo di Russo3, Roberta Morace3
1Department of Neurosurgery, IRCCS Neuromed, Pozzilli, IS, Italy. arianna.f.90@gmail.com.
Background:
Gross total resection, when possible, is the first crucial treatment for high-grade gliomas, as it has been demonstrated to be associated with longer survival. Different intraoperative tools, such as neuronavigation, fluorescent agents, and intra-operative ultrasound, have been developed to help neurosurgeons to extend the resection.
Methods:
We describe the high-magnification microsurgery technique used during the first surgical removal for high-grade gliomas. We illustrate the key anatomical "markers" of normal brain parenchyma, which guide the surgery.
Conclusion:
High-magnification microsurgery is an anatomically based approach that allows the identification of key anatomical "markers" of normal brain parenchyma in order to resect high-grade gliomas safely and effectively.
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