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Characterization of Immune Cell-derived Extracellular Vesicles and Studying Functional Impact on Cell Environment
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The cellular response to extracellular vesicles is dependent on their cell source and dose

Daniel W Hagey1,2, Miina Ojansivu3, Beklem R Bostancioglu1,2

  • 1Department of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.

Science Advances
|September 1, 2023
PubMed
Summary

Cellular responses to extracellular vesicles (EVs) depend more on dose than source. High doses alter exocytosis and lysosomal activity, while low doses reveal source-specific effects, impacting cell communication and therapy potential.

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