Related Experiment Video
Updated: Jul 17, 2025

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
Published on: October 14, 2016
Current Challenges of Asian National Children's Cancer Study Groups on Behalf of Asian Pediatric Hematology and
Chi-Kong Li1, Purna Kurkure2, Ramandeep Singh Arora3
1Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong Children's Hospital, Hong Kong SAR, China.
Insights
Establishing national pediatric cancer study groups in Asia faces challenges like healthcare affordability and research staff shortages. The Asian Pediatric Hematology and Oncology Group aims to foster international clinical trials across the region.
Area of Science:
- Pediatric Oncology
- Clinical Trial Management
- Health Systems Research
Background:
- Many Asian countries lack established national pediatric cancer study groups, hindering collaborative clinical trials.
- Forming these groups involves country-specific hurdles, impacting research infrastructure.
- Variations in healthcare affordability and insurance coverage for childhood cancer affect treatment accessibility and trial feasibility.
Purpose of the Study:
- To highlight the challenges in establishing national pediatric cancer study groups in Asia.
- To identify key barriers including healthcare system affordability and insurance coverage.
- To introduce the Asian Pediatric Hematology and Oncology Group as a platform to promote international clinical trials.
Main Methods:
- The study discusses the general landscape and challenges of forming pediatric cancer study groups in Asia.
- It analyzes factors such as healthcare system affordability and insurance coverage.
- It also addresses the common issue of research personnel shortages.
Main Results:
- Significant disparities exist in health insurance coverage for children with cancer across Asian nations.
- Shortages of essential research personnel (medical, nursing, coordinators, data managers) are prevalent.
- These factors collectively impede the successful operation of clinical trials.
Conclusions:
- The formation of national pediatric cancer study groups in Asia is complex and requires addressing healthcare and staffing issues.
- The Asian Pediatric Hematology and Oncology Group is established to facilitate international collaboration and improve clinical trial infrastructure.
- Overcoming these barriers is crucial for advancing pediatric cancer research and treatment in Asia.
Abstract:
In Asia, a few countries have a long and established history of collaborative clinical trials successfully formed national children's cancer study groups, but many still do not have such groups. The process of forming national children's cancer groups is fraught with many hurdles, which varies among the countries. One of the basic requirements for running clinical trials is an affordable health care system in which most of the children with cancer can receive the proposed treatment. The health insurance coverage for children with cancer varies from <20% to as high as 100% among Asian countries, and the operation of clinical trials must also be adjusted accordingly. Shortage of research personnel is common, including medical, nursing, research coordinators, and data managers. The establishment of the Asian Pediatric Hematology and Oncology Group aims to provide a good platform for promotion of international clinical trials in the Asian countries.
Related Concept Videos
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
Treatment Resistant Cancers
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
National Nursing Organizations II
The AACN emphasizes a healthy work environment through six standards to achieve an optimal patient outcome. The standards are appropriate staffing, meaningful recognition, collaboration, authentic leadership, effective communication, and decision-making. In addition, AACN provides certification programs, webinars, journals, and...
Targeted Cancer Therapies
There are several types of targeted therapies against...

