Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

327
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
327

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Robust and well-structured graphene oxide membranes crosslinked by phenylboronic acid for efficient heavy metal ion sieving.

Nanoscale·2026
Same author

Machine learning-based prediction model for adverse pregnancy outcomes in women with gestational diabetes mellitus.

Journal of diabetes investigation·2026
Same author

A Case of SREBF1-Associated Ichthyosis Follicularis, Alopecia, and Photophobia Syndrome With Recurrent Alopecia.

The Journal of dermatology·2026
Same author

Long-term Particulate Matter Exposure and Risk of Alopecia Areata: A Nationwide Epidemiological Study with Preliminary In Vitro Evidence.

The British journal of dermatology·2026
Same author

Quercetin Alleviates Intestinal and Liver Dysfunction Induced by Hypoxia in a Microphysiological System.

ACS biomaterials science & engineering·2026
Same author

Bioelectrical impedance-derived extracellular fluid expansion and perinatal outcomes in preeclampsia.

Hypertension in pregnancy·2026

Related Experiment Video

Updated: Jul 17, 2025

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions
05:13

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions

Published on: June 21, 2024

892

Creating mini-pregnancy models in vitro with clinical perspectives.

Jee Yoon Park1, Hosub Lim2, Jianhua Qin3

  • 1Department of Obstetrics and Gynecology, Seoul National University, Bundang Hospital, Seoul National University College of Medicine, Republic of Korea; Department of Medicine, Harvard Medical School, Brigham Women's Hospital, Boston, MA, USA.

Ebiomedicine
|September 1, 2023
PubMed
Summary

Bioengineering is recreating human pregnancy using organs-on-chips. This approach aids in developing treatments for pregnancy diseases and monitoring drugs, advancing precision medicine.

Keywords:
Microphysiological systemOrganoidsOrgans-on-a-chipPlacentaPregnancyTrophoblast

More Related Videos

Author Spotlight: In Vitro Endometrial Models to Study Epithelial-Stroma and Embryo Interactions
05:58

Author Spotlight: In Vitro Endometrial Models to Study Epithelial-Stroma and Embryo Interactions

Published on: November 8, 2024

665
Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

1.7K

Related Experiment Videos

Last Updated: Jul 17, 2025

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions
05:13

Author Spotlight: Advancing Therapeutic Strategies for Improving Pregnancy Rates by Analyzing Embryo-Endometrium Interactions

Published on: June 21, 2024

892
Author Spotlight: In Vitro Endometrial Models to Study Epithelial-Stroma and Embryo Interactions
05:58

Author Spotlight: In Vitro Endometrial Models to Study Epithelial-Stroma and Embryo Interactions

Published on: November 8, 2024

665
Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model
06:49

Methods for Studying Uterine Contributions to Pregnancy Establishment in an Ovariectomized Mouse Model

Published on: April 7, 2023

1.7K

Area of Science:

  • Bioengineering
  • Maternal-Fetal Medicine
  • Developmental Biology

Background:

  • Ethical limitations restrict research on pregnant women.
  • In vitro models of human pregnancy are crucial for developing new treatments.
  • Microphysiological analysis platforms (MAPs) like organs-on-chips show promise.

Purpose of the Study:

  • To review bioengineering efforts in recreating human pregnancy.
  • To highlight advancements in culturing pregnancy-related cells and tissues.
  • To examine bioengineering solutions for pregnancy-associated diseases.

Main Methods:

  • Reviewing recent achievements in culturing placental trophoblasts.
  • Highlighting developments in reconstituting pregnancy-related organs in vitro.
  • Examining research on pregnancy-associated diseases and bioengineering solutions.

Main Results:

  • Progress has been made in culturing key pregnancy tissues, such as trophoblasts.
  • Various structural and functional interpretations of pregnancy-related organs are being reconstituted.
  • Bioengineering approaches are being explored to understand and address pregnancy diseases.

Conclusions:

  • Recreating human pregnancy via engineered models is complex but essential for advancing precision medicine.
  • The convergence of biology, engineering, and maternal-fetal medicine is key to progress.
  • Engineered models offer a path for drug monitoring and disease modeling in pregnancy.