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Updated: Jul 17, 2025

A Package of Established Analytical Tools to Investigate the Solid-State Alteration of Lipid-Based Excipients
Published on: August 9, 2022
Solid-state analysis for pharmaceuticals: Pathways to feasible and meaningful analysis
Jukka Rantanen1, Thomas Rades1, Clare Strachan2
1Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
Abstract:
The solid state of matter is the preferred starting point for designing a pharmaceutical product. This is driven by both patient preferences and the relative ease of supplying a solid pharmaceutical product with desired quality and performance. Solid form diversity is increasingly prevalent as a crucial element in designing these products, which underpins the importance of solid-state analytical methods. This paper provides a critical analysis of challenges related to solid-state analytics, as well as considerations and suggestions for feasible and meaningful pharmaceutical analysis.
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