Related Experiment Video

Updated: Jul 17, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
09:52

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Published on: March 16, 2018

9.5K

[Intratympanic Drug Application - Indication and Procedure]

Lena Zaubitzer, Nicole Rotter, Angela Schell

    Laryngo- Rhino- Otologie
    |September 1, 2023
    PubMed
    Summary

    Intratympanic drug administration offers a simple, cost-effective treatment for inner ear neurootologic disorders like tinnitus and vertigo. This outpatient therapy has minimal side effects and should be considered when appropriate.

    More Related Videos

    A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection09:18

    A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection

    Published on: March 8, 2017

    13.3K
    A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus06:55

    A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus

    Published on: February 27, 2018

    8.7K

    Related Concept Videos

    Drug Delivery: Parenteral Route01:29

    Drug Delivery: Parenteral Route

    The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
    There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
    608
    Additional Routes of Drug Administration01:18

    Additional Routes of Drug Administration

    Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
    Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...
    2.8K
    Drug Delivery: Miscellaneous Routes01:22

    Drug Delivery: Miscellaneous Routes

    Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
    Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
    Transdermal patches transport drugs...
    379
    Endotracheal Intubation I: Procedure01:15

    Endotracheal Intubation I: Procedure

    Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
    The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
    1.6K
    Assessing Body Temperature - Tympanic membrane01:14

    Assessing Body Temperature - Tympanic membrane

    Assessing tympanic membrane temperature involves using a tympanic membrane thermometer (TMT). Here is a step-by-step guide:
    Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
    Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
    Step 3: Slide the probe cover in place to prevent cross-contamination.
    Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
    610
    Drug Delivery: Enteral Route01:18

    Drug Delivery: Enteral Route

    The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
    503