Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Delivery: Parenteral Route01:29

Drug Delivery: Parenteral Route

608
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
608
Additional Routes of Drug Administration01:18

Additional Routes of Drug Administration

2.8K
Choosing the appropriate route of drug administration is significantly influenced by two key factors: the therapeutic objectives and the inherent properties of the drug being used.
Administering drugs via inhalation allows for the direct delivery of gaseous, volatile substances or droplets to different parts of the respiratory tract. One of the advantages of the inhalation route is the rapid absorption of drugs into the circulatory system, which is possible because of the large surface area of...
2.8K
Drug Delivery: Miscellaneous Routes01:22

Drug Delivery: Miscellaneous Routes

379
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection,  and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
379
Endotracheal Intubation I: Procedure01:15

Endotracheal Intubation I: Procedure

1.6K
Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
1.6K
Assessing Body Temperature - Tympanic membrane01:14

Assessing Body Temperature - Tympanic membrane

610
Assessing tympanic membrane temperature involves using a tympanic membrane thermometer (TMT). Here is a step-by-step guide:
Step 1: Begin by practicing good hand hygiene to prevent the transmission of microorganisms.
Step 2: Turn on the thermometer and wait until the ready sign appears on the screen to ensure accurate measurement.
Step 3: Slide the probe cover in place to prevent cross-contamination.
Step 4: Instruct the patient to tilt their head to the side for comfort and check for cerumen...
610
Drug Delivery: Enteral Route01:18

Drug Delivery: Enteral Route

503
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
503

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Awareness of Head and Neck Cancer, its Risk Factors, and of Human Papillomavirus-A Survey Study.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale·2026
Same author

Automated Pretreatment Thoracic CT-Based Body Composition Analysis Predicts Progression-Free Survival in Head and Neck Cancer.

Journal of clinical medicine·2026
Same author

"When patients see what the surgeon sees": 3D imaging creates new understanding in preoperative counseling for endoscopic sinus surgery.

Acta oto-laryngologica·2026
Same author

Systemic inflammation plays a key prognostic role in patients with head and neck cancer treated with immunotherapy and is linked to CT-based body composition metrics.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·2026
Same author

Muscle matters: automated CT-based body composition analysis predicts survival in patients with head and neck cancer treated with immunotherapy.

Frontiers in oncology·2026
Same author

Bicentric evaluation of employee satisfaction, patient safety and treatment quality: comparing different Health Information System (HIS) solutions.

BMC health services research·2025

Related Experiment Video

Updated: Jul 17, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
09:52

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

Published on: March 16, 2018

9.5K

[Intratympanic Drug Application - Indication and Procedure].

Lena Zaubitzer, Nicole Rotter, Angela Schell

    Laryngo- Rhino- Otologie
    |September 1, 2023
    PubMed
    Summary
    This summary is machine-generated.

    Intratympanic drug administration offers a simple, cost-effective treatment for inner ear neurootologic disorders like tinnitus and vertigo. This outpatient therapy has minimal side effects and should be considered when appropriate.

    More Related Videos

    A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
    09:18

    A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection

    Published on: March 8, 2017

    13.3K
    A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus
    06:55

    A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus

    Published on: February 27, 2018

    8.7K

    Related Experiment Videos

    Last Updated: Jul 17, 2025

    Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
    09:52

    Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity

    Published on: March 16, 2018

    9.5K
    A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection
    09:18

    A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection

    Published on: March 8, 2017

    13.3K
    A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus
    06:55

    A Surgical Procedure for the Administration of Drugs to the Inner Ear in a Non-Human Primate Common Marmoset Callithrix jacchus

    Published on: February 27, 2018

    8.7K

    Area of Science:

    • Otolaryngology
    • Neurotology
    • Pharmacology

    Context:

    • Neurootologic disorders, including tinnitus, vertigo, and hearing loss, are prevalent and distressing.
    • Current treatment options for these inner ear conditions are often limited.

    Purpose:

    • To highlight intratympanic drug administration as a viable treatment option for specific neurootologic indications.
    • To emphasize the benefits of this therapeutic approach.

    Summary:

    • Intratympanic drug administration involves delivering medication directly into the middle ear.
    • This method is characterized by its simplicity, low cost, and minimal side effects.
    • It is suitable for outpatient settings and offers a practical alternative for managing inner ear disorders.

    Impact:

    • Intratympanic therapy provides a potentially effective and accessible treatment modality for patients suffering from debilitating neurootologic symptoms.
    • This approach can improve patient quality of life by managing conditions like tinnitus and vertigo.