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Mpox: Keep it on the differential.

Sara L Clemens1, Stuart N Isaacs2

  • 1Infectious Diseases Fellow, Hospital of the University of Pennsylvania, Philadelphia, PA.

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Summary
This summary is machine-generated.

Mpox outbreaks present new clinical signs clinicians must recognize. Though cases decline, mpox may persist or re-emerge, requiring its inclusion in differential diagnoses for patients with potential infections after intimate contact.

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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • The recent global mpox outbreak revealed atypical clinical manifestations.
  • Awareness of these novel presentations is crucial for timely diagnosis and patient care.

Purpose of the Study:

  • To inform clinicians about the evolving clinical spectrum of mpox.
  • To emphasize the importance of considering mpox in differential diagnoses.

Main Methods:

  • This study is based on observations and clinical data from the global mpox outbreak.

Main Results:

  • Mpox has displayed several previously undocumented clinical features during the current outbreak.
  • While case rates have fallen, the virus may persist endemically or reappear in different demographics.

Conclusions:

  • Clinicians must be vigilant for unusual mpox presentations.
  • Mpox should remain a consideration in patients with symptoms suggestive of infection following intimate encounters, even with decreased overall incidence.