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Updated: Aug 19, 2026

Intracortical Inhibition Within the Primary Motor Cortex Can Be Modulated by Changing the Focus of Attention
Published on: September 11, 2017
[Systems mechanisms of internal inhibition]
Abstract:
The state of internal inhibition is analysed which is considered as a multifactor systemically organized process. On model of combined presentation of positive and inhibitory stimuli in experiments on white rats and dogs, a dependence is established of the efficiency of reinforcement cancellation factor on motivation intensity. Condition of negative emotion--frustration, "difficult state"-is a necessary link in the process of internal inhibition formation, since it is responsible for selection of non-reinforcement for storage in the long-term memory. Conclusion is made that active inhibition of goal-directed behaviour is mediated by actualization of memory trace, "engram of non-reinforcement" by negative conditioned stimulus.
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