Short-pulse laser plus subthreshold diffuse laser for serous retinal detachment in dome-shaped macula

Area of Science:

• Ophthalmology
• Retinal Diseases
• Medical Technology

Background:

• Dome-shaped macula (DSM) is characterized by an anterior convex protrusion of the macula.
• Visual impairment in DSM often results from sub-foveal serous retinal detachment (SRD).
• Current treatments focus on addressing SRD to improve visual function.

Purpose of the Study:

• To evaluate the anatomical and functional outcomes of a combined laser treatment for SRD in patients with DSM.
• To assess the efficacy of Pascal® short-pulse (SP) laser combined with endpoint management (EpM) subthreshold diffuse laser (SDL).

Main Methods:

• Retrospective analysis of seven consecutive patients (eight eyes) with SRD secondary to DSM.
• Ophthalmological evaluation including visual acuity (BCVA) and spectral-domain optical coherence tomography (SD-OCT).
• Treatment involved combined Pascal® SP laser plus EpM-SDL, with follow-up intervals of 1-6 months and a mean follow-up of 12.92 months.

Main Results:

• Significant reduction in central subfield thickness (CST) from 412.50 µm to 294.75 µm (p=0.0078).
• Significant improvement in best-corrected visual acuity (BCVA) from 0.6125 LogMAR to 0.4537 LogMAR (p=0.0313).
• Mean SRD resolution time was 3.75 months, with no adverse events reported.

Conclusions:

• The combined Pascal® SP laser plus EpM-SDL treatment is a novel modality for managing SRD in DSM patients.
• This treatment can induce subretinal fluid regression and improve BCVA within one year.
• The procedure demonstrated safety and efficacy in the studied patient cohort.