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Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
Published on: September 30, 2020
Post-COVID-19 Intensive Care Unit-Acquired Weakness Compromises Long-Term Functional Status
Débora Schmidt1,2, Ane Glauce Margarites1, Letícia Pinto Krás Borges Alvarenga1
1Physical Therapy Service, Hospital de Clínicas de Porto Alegre (HCPA), Santa Cecília, Porto Alegre, Rio Grande do Sul, Brazil.
Patients hospitalized for coronavirus disease 2019 (COVID-19) often experience long-term functional decline after intensive care unit (ICU) discharge. Intensive care unit-acquired weakness (ICUAW) significantly worsens these outcomes over six months.
Area of Science:
- Critical Care Medicine
- Infectious Diseases
- Rehabilitation Medicine
Background:
- Coronavirus disease 2019 (COVID-19) survivors frequently experience prolonged recovery.
- Intensive care unit (ICU)-acquired weakness (ICUAW) is a known complication impacting patient recovery.
- The long-term functional consequences of COVID-19 hospitalization, particularly concerning ICUAW, require further investigation.
Purpose of the Study:
- To assess the impact of ICUAW on functional independence in COVID-19 patients.
- To evaluate functional status up to six months post-ICU discharge.
- To identify specific challenges faced by COVID-19 survivors with ICUAW.
Main Methods:
- Prospective cohort study of COVID-19 patients admitted to the ICU.
- Telephone-based follow-up at 30 days, 3 months, and 6 months post-ICU discharge.
- Assessment of functional independence using validated scales (Barthel Scale, Katz Index, PCFS, ICU Mobility Scale).
- Diagnosis of ICUAW based on Medical Research Council score <48 at ICU discharge.
Main Results:
- 35% of patients developed ICUAW.
- At six months post-ICU discharge, 38.2% of patients still had functional limitations.
- Patients with ICUAW showed a significantly higher rate of persistent functional limitations (66.7%) compared to those without (22.8%).
- Moderate to severe functional limitations were also more prevalent in the ICUAW group.
Conclusions:
- Functional independence remains compromised for a significant period after ICU discharge for COVID-19 survivors.
- ICUAW is associated with poorer functional outcomes and prolonged dependence.
- Early identification and management of ICUAW are crucial for improving long-term recovery in COVID-19 patients.
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