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Published on: September 28, 2019
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Continuous irrigation after pancreatectomy: a systematic review.
Ilaria Pergolini1,2,3, Florian Scheufele1,2,3, Elke Demir1,2,3
1Department of Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Straße 22, 81675, Munich, Germany.
Langenbeck'S Archives of Surgery
|September 2, 2023
Summary
Continuous irrigation may help prevent and manage postoperative pancreatic fistula (POPF) after pancreatic surgery. This technique showed promising results in reducing complications and mortality in high-risk patients, warranting further investigation.
Area of Science:
- Surgical Oncology
- Gastroenterology
- Pancreatic Surgery
Background:
- Postoperative pancreatic fistula (POPF) remains a significant challenge after pancreatic resections.
- The efficacy of continuous irrigation in the peripancreatic area following elective pancreatic surgery is not well-established.
Approach:
- A systematic literature review was conducted following PRISMA 2020 guidelines.
- Databases searched included Pubmed, Scopus, Web of Science, and Ovid MEDLINE.
- Due to study heterogeneity, a descriptive review was performed; no statistical inference was possible.
Key Points:
- Three studies on prophylactic irrigation after distal pancreatectomy showed lower rates of clinically relevant POPF, complications, and mortality.
- Six studies on local lavage for treating POPF reported successful outcomes.
- Continuous irrigation may reduce length of hospital stay.
Conclusions:
- Limited publications exist on continuous irrigation for POPF prevention/management post-pancreatic resection.
- Promising results suggest potential utility in high-risk patients.
- Further research, including randomized trials, is necessary to confirm efficacy.
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