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Related Experiment Video

Updated: Jul 17, 2025

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy
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Continuous irrigation after pancreatectomy: a systematic review.

Ilaria Pergolini1,2,3, Florian Scheufele1,2,3, Elke Demir1,2,3

  • 1Department of Surgery, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Straße 22, 81675, Munich, Germany.

Langenbeck'S Archives of Surgery
|September 2, 2023
PubMed
Summary

Continuous irrigation may help prevent and manage postoperative pancreatic fistula (POPF) after pancreatic surgery. This technique showed promising results in reducing complications and mortality in high-risk patients, warranting further investigation.

Keywords:
Continuous irrigationPancreatic fistulaPancreatic surgery

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Area of Science:

  • Surgical Oncology
  • Gastroenterology
  • Pancreatic Surgery

Background:

  • Postoperative pancreatic fistula (POPF) remains a significant challenge after pancreatic resections.
  • The efficacy of continuous irrigation in the peripancreatic area following elective pancreatic surgery is not well-established.

Approach:

  • A systematic literature review was conducted following PRISMA 2020 guidelines.
  • Databases searched included Pubmed, Scopus, Web of Science, and Ovid MEDLINE.
  • Due to study heterogeneity, a descriptive review was performed; no statistical inference was possible.

Key Points:

  • Three studies on prophylactic irrigation after distal pancreatectomy showed lower rates of clinically relevant POPF, complications, and mortality.
  • Six studies on local lavage for treating POPF reported successful outcomes.
  • Continuous irrigation may reduce length of hospital stay.

Conclusions:

  • Limited publications exist on continuous irrigation for POPF prevention/management post-pancreatic resection.
  • Promising results suggest potential utility in high-risk patients.
  • Further research, including randomized trials, is necessary to confirm efficacy.