Use of eye tracking to improve the identification of attention-deficit/hyperactivity disorder in children

Dong Yun Lee1,2, Yunmi Shin3, Rae Woong Park1,4

  • 1Department of Biomedical Informatics, Ajou University School of Medicine, Suwon, Republic of Korea.

Scientific Reports
|September 2, 2023
PubMed

Insights

Eye-tracking combined with continuous performance tests (CPTs) significantly improves the diagnosis of attention-deficit/hyperactivity disorder (ADHD) in children. This approach offers higher accuracy than CPTs alone and shows improvement with medication.

Area of Science:

  • Neurodevelopmental disorders
  • Pediatric neurology
  • Diagnostic technologies

Background:

  • Attention-deficit/hyperactivity disorder (ADHD) is a common childhood neurodevelopmental disorder requiring early detection.
  • Current diagnostic methods like continuous performance tests (CPTs) have limitations in efficacy.
  • Eye movement patterns may provide valuable diagnostic insights for ADHD.

Purpose of the Study:

  • To compare the diagnostic performance of eye-tracking and CPTs, individually and combined, for ADHD in children.
  • To evaluate the impact of ADHD medication on eye movement and CPT outcomes.

Main Methods:

  • Recruited 60 children (aged 6-10) into ADHD and healthy control groups.
  • Administered eye-tracking assessments and CPTs to all participants.
  • Analyzed diagnostic accuracy using receiver operating characteristic (ROC) curves and evaluated medication effects.

Main Results:

  • Combined eye-tracking and CPTs achieved a higher area under the ROC curve (AUC=0.889) for ADHD identification compared to CPTs alone (AUC=0.769).
  • Eye-tracking alone demonstrated superior performance (AUC=0.856) over CPTs alone (AUC=0.769, p=0.029).
  • Significant improvements in eye-tracking and CPT metrics were observed after medication administration.

Conclusions:

  • Eye movement analysis, particularly when integrated with CPTs, can enhance diagnostic precision for ADHD in children.
  • Eye-tracking offers a promising tool for differentiating children with ADHD.
  • Medication positively influences both eye movement patterns and CPT performance in children with ADHD.